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Cerebellar ataxia

 52 /M , saree weaver by occupation presented with h/o slurring of speech ,deviation of mouth -that lasted for 1 day and resolved on same day . Brain imagining was done which showed cerebellar infarct and denovo HTN + patient was asked to continue medication regularly but he didn’t 

He is chronic smoker 1 pack of beedi/day and chronic alcoholic since 30 years consumes 90 -180 of Ib thrice weekly 

Pt gives h/o - giddiness -5 days back at 7 am in the morning pt was on routine works and suddenly at 7am .pt felt giddiness and took rest .it was associated with 1 episode of vomiting  on the same day pt had h/o  postural instability , while walking to and was about fall no seizure like activity

Pt was assyptomatic for 3 days then he consumed small amount of alcohol 

Pt was assymptomatic till 3pm then the patient developed -giddiness , sudden onset and gradually progressive , continuous and increased on getting up from bed , while walking , associated with B/L hearing loss , aural fullness , tinnitus present 

Postural instability - unable to walk without supports swaying present 

Vomitings - 2-3 episodes /day , nonprojectile ,non bilious containing food particles 

No diplopia , dysphagia , dysarthria , deviation of mouth , weakness of Limbs , bladde and bowel incontinence , no sensory symptoms 

CNS 
Hmf- intact 
Motor system 
                         Rt.           Lt 
Tone ul             N             N 
Tone ll.             N.            N 
Power ul.         5/5.          5/5 
           Ll.         5/5.          5/5 
Reflexes          +2            +2 
Gait - wait based - ataxic gait 
Cranial nerves - 
8th - Rennes  bc>ac.     Ac> bc 
Weber’s - no lateralisation 
NYSTAGMUS- Bilateral horizontal nystagmus, vertical upbeat nystagmus, more on right lateral position with a fast component to the left. 





INVESTIGATIONS:

COMPLETE URINE EXAM:
Colour- Pale yellow
Appearance- cloudy
Reaction- Acidic
Sp. Gravity- 1.010
Albumin- +
Sugar- nil
Bile salts- Nil
Bile pigments- Nil
Pus cells- 3-4
Epithelial cells- 2-3
Red blood cells- Nil
Crystals- Nil
Casts- Nil
Amorphous deposits- Absent
Others- Nil

RFT:
Urea- 28 mg/dl
Creatinine- 0.9 mg/dl
Uric acid- 7.4 mg/dl
Calcium- 9.8 mg/dl
Phosphorous- 1.3 mg/dl
Sodium- 140 mEq/L
Potassium- 3.5 mEq/L

LIVER FUNCTION TESTS:
Total Bilirubin- 2.00 mg/dl
Direct bilirubin- 0.55 mg/dl
SGOT (AST)- 17 IU/L
SGPT (ALT)- 18 IU/L
Alkaline phosphatase- 187 IU/L
Total proteins- 7.2 g/dl
Albumin- 4.5 g/dl
A/G Ratio- 1.72


CT SCAN- Computed tomography scan of the brain was done, which revealed a cerebellar infarct.  
     





2D ECHO- Done on 19/05/21, shows good LV systolic function
No MS/AS
Diastolic Dysfunction present 

PROVISIONAL DIAGNOSIS:

Cerebellar Ataxia secondary to Acute Cerebrovascular Accident (CVA) with infarct in the right inferior cerebellar hemisphere.



TREATMENT HISTORY:

Tab Veratin 8 mg PO TID

Inj Zofer 4 mg IV/TID

Tab Ecosprin 75 mg PO/OD

Tab Atorvostatin 40 mg PO/HS

BP monitoring- 4rth hourly

Tab Clopidogrel 75 mg PO/OD

Inj Thiamine 1 AMP in 100 ml NSPO/BD

Tab MVT PO/OD


ADVICE ON DISCHARGE-

Tab Vertin 8 mg PO TID - 1 week

Tab Zofer 4 mg IV/TID - 1 week

Tab Ecosporin 75 mg PO/OD - 1 week

Tab Atorvostatin 40 mg PO/HS - 1 week

Tab Clopidogrel 75 mg PO/OD - 1 week

Tab MVT PO/OD - 1 week


FOLLOW UP-

Review to OPD after 10 days 



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 INVESTIGATIONS:


COMPLETE URINE EXAM:
Colour- Pale yellow
Appearance- cloudy
Reaction- Acidic
Sp. Gravity- 1.010
Albumin- +
Sugar- nil
Bile salts- Nil
Bile pigments- Nil
Pus cells- 3-4
Epithelial cells- 2-3
Red blood cells- Nil
Crystals- Nil
Casts- Nil
Amorphous deposits- Absent
Others- Nil

RFT:
Urea- 28 mg/dl
Creatinine- 0.9 mg/dl
Uric acid- 7.4 mg/dl
Calcium- 9.8 mg/dl
Phosphorous- 1.3 mg/dl
Sodium- 140 mEq/L
Potassium- 3.5 mEq/L

LIVER FUNCTION TESTS:
Total Bilirubin- 2.00 mg/dl
Direct bilirubin- 0.55 mg/dl
SGOT (AST)- 17 IU/L
SGPT (ALT)- 18 IU/L
Alkaline phosphatase- 187 IU/L
Total proteins- 7.2 g/dl
Albumin- 4.5 g/dl
A/G Ratio- 1.72


CT SCAN- Computed tomography scan of the brain was done, which revealed a cerebellar infarct.  
     





2D ECHO- Done on 19/05/21, shows good LV systolic function
No MS/AS
Diastolic Dysfunction present 

PROVISIONAL DIAGNOSIS:

Cerebellar Ataxia secondary to Acute Cerebrovascular Accident (CVA) with infarct in the right inferior cerebellar hemisphere.



TREATMENT HISTORY:

Tab Veratin 8 mg PO TID

Inj Zofer 4 mg IV/TID

Tab Ecosprin 75 mg PO/OD

Tab Atorvostatin 40 mg PO/HS

BP monitoring- 4rth hourly

Tab Clopidogrel 75 mg PO/OD

Inj Thiamine 1 AMP in 100 ml NSPO/BD

Tab MVT PO/OD


ADVICE ON DISCHARGE-

Tab Vertin 8 mg PO TID - 1 week

Tab Zofer 4 mg IV/TID - 1 week

Tab Ecosporin 75 mg PO/OD - 1 week

Tab Atorvostatin 40 mg PO/HS - 1 week

Tab Clopidogrel 75 mg PO/OD - 1 week

Tab MVT PO/OD - 1 week


FOLLOW UP-

Review to OPD after 10 days 



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