65 year old male with anasarca

 

65 YEAR OLD MALE WITH ANASARCA


 

65 year old male came to the casuality on at 3:30pm on 8/11/21

with

c/o b/l pedal edema since 10 days 

c/o shortness of breath since 4   days

c/o facial puffiness since 2 days  

c/o decreased appetite since 2 days

c/o decreased urine output 


Patient was  apparently asymptomatic 3 years ago, then he developed Rt sided hemiparesis and was diagnosed with CVA and was on antiplatelets on and off.

He was also diagnosed with DM at that time and HTN one year later 

Patient has c/o pedal edema ( upto knee, decreasing on rest ) and shortness of breath ( grade II-III ) since 1 1/2 year and was diagnosed with chronic kidney disease 1 1/2 years ago and is on regular medication.

No dialysis was done. Managed conservatively.


C/o pedal edema since 10 days gradually progressed toward face 

(Pitting type)

C/o shortness of breath (grade II-III)

since 4 days 

Facial puffiness since 2 days 

A/w loss of appetite and decreased urine output 

Not a/w orthopnea, PND 


The patient has been married for 31 years and has two daughters (30 yrs and 26 yrs). He is a Village revenue officer by occupation.

He used to go to work everyday and was able to perform all his daily activities on his own. Even after his CVA which caused rt hemiparesis 3 years ago, he used to go to work everyday post his recovery 

But since about 1 1/2 year ago he is not able to go to work regularly due to his swollen

feet and has been going to work only when he had meetings to attend. He completely stopped going to work since the past few months.

Even during this time he was able to perform his day to day activities at home on his own until 10 days ago when he started

developing extensive swelling, staring in his feet, gradually progressing to his entire body when he couldn’t even stand up on his own and needed help from a family member for all his daily activities.

Even his speech became unclear since the past few days.



K/C/O 

DM since 3 years - on human actrapid 

15U——x——-8U

HTN since 11/2 year- on Tab. Met XL

CAD



Personal:

Diet-mixed 

Appetite - reduced 

Sleep - reduced

Bowel and Bladder- decreased urine output

Addictions-

non smoker 

Alcohol + but stopped since 3 years 



Vitals:

Temp- 97.7F

BP- 160 / 90 mmhg

PR- 98 bpm

RR- 24 cpm 

Spo2-98%

GRBS- 184 mg/dl


O/E- 

Pallor +

Edema + pitting type (anasarca) 

No Icterus, cyanosis, clubbing, lymphadenopathy.

                             Weight - 75 kgs 


CVS- S1 S2 +

RS- BAE+ crepts + 

Dyspnea +

Wheeze +

P/A- distended, non tender 

Free fluid +

CNS- NAD



Investigations:

Hb-9.4

TLC- 6000

PLC- 2.09 lakhs 


CUE:

Alb- +++

Sug- trace 

PC- 3-5

EC- 2-4


RBS- 184 mg/dl

HbA1C- 6.7 %


Urea-139

Creat-5.3

Uric acid-5.8

Na-141

K-5.6

Cl-101


TB- 0.94

DB- 0.13

AST- 10 

ALT- 09

ALP- 308

TP-5.1

Alb- 2.5

A/G- 1.02 


ABG

PH- 7.124

pCo2- 29.4

PO2- 116

HCO3- 9.3


Spot Urine protein creat ratio- 4.97

Serum LDH- 632

Urinary Na- 198

Urinary K- 16.5

Urinary Cl- 409


HIV, HbSAg, HCV, RAT for COVID 19- negative 


ECG:    

X Ray chest:

Rt sided pleural effusion with consolidation.



2D echo:

Global hypokinesia 

EF- 32%

Severe LV dysfunction 

Dilated all chambers 

IVC dilated ( 2.25 cms )


USG :

RT gross pleural effusion 

Lt moderate pleural effusion 

Gall bladder sludge +

B/L grade II RPD

Moderate ascites.


Diagnosis:

Acute LVF ( secondary to HTN) on chronic heart failure ( secondary to CAD)

K/c/oChronic kidney disease

K/c/o DM, HTN, CAD.


Treatment:

Fluid restriction 

Inj Lasix 40 mg / IV / Stat followed by inj Lasix 20 mg @ 2.5 ml / hr

Inj Pantop 40 mg IV/OD

Inj Zofer 4 mg IV/SOS 

Nebulisation with duolin and budecort 8th hourly 

Tab Ecosprin AV ( 75/ 20 ) PO/ H/S

Tab Amlong 10 mg PO/ H/S

Inj HAI S/C pre meal acc to sliding scale 

Weight monitoring daily 

Foleys catherisation done 


Pleural tap done I/v/o Rt sided gross pleural effusion


Pleural fluid analysis:

Sugar- 198
Protein- 0.7
LDH- 154





Post pleural tap chest X Ray


I/o -50/400 ml .

Plan - Hemodialysis in view of Severe metabolic acidosis 

And hyperkalemia ( serum K -6 )

Hemodialysis was done for 3 hours 

Ultrafiltrate removed- 500 ml


Day 3:


AMC bed 7, Unit 1

65/M

Day 3


S:

SOB decreased

EDEMA decreased

No fever spikes.

Didn't pass stools.

1serial HD done.


O:

Pt is c/c/c

Temp-98.4f

Bp: 130/70mmhg

PR: 84 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA,ISA.

P/A: soft,non tender

GRBS: 176 mg/dl

I/O: 450/350ml

SPO2: 95%

CNS: HMF INTACT


ABG:


PH: 7.243

PCO2: 33.8

PO2: 134

HCO3: 14.0


HEMOGRAM:


HB: 8.4

TC: 7000

PLT: 1.40

RFT:


UREA: 74

CREATININE: 3.1

UA: 3.3

Ca: 7.0

Po4: 3.4

Na: 148

K: 3.4

Cl: 102


LFT:


TB: 0.56

DB: 0.20

AST: 10

ALT: 11

ALP: 133

TP: 3.1

ACB: 1.5

A/G ratio : 0.91



A:


ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).


with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs


With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)


With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)


with REFRACTORY HYPERKALEMIA ( RESOLVING).


P:


Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Pantop 40mg /i.v/od

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD

Tab Shelcal PO/OD

Plan for hemodialysis


AMC bed 7, Unit 1

65/M

Day 4


S:

SOB decreased

EDEMA decreased

No fever spikes.


1 session  HD done on 10/11/21


O:

Pt is c/c/c

Temp-99.0F

Bp: 130/80 mmhg 

PR: 96 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA,ISA.

P/A: soft,non tender

GRBS: 158 mg/dl

I/O: 700ml/500 ml

SPO2: 98% @ RA

CNS: HMF INTACT





ABG:

PH: 7.278

PCO2: 39.1

PO2: 70.0

HCO3: 17.7


HEMOGRAM:


HB: 7.5

TC: 6,100

PLT: 1.5 lakhs


RFT:


UREA: 73

CREATININE: 3.3

UA: 3.6

Ca: 7.6

Po4: 3.4

Na: 148

K: 4.0

Cl: 101


A:


ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).


with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs


With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)


With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)


with REFRACTORY HYPERKALEMIA ( RESOLVING).


With ANEMIA 



P:


Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD

Tab Shelcal PO/OD


AMC bed 7, Unit 1

65/M

Day 5


S:

SOB decreased

EDEMA decreased

No fever spikes.


2 sessions of hemodialysis done 


O:

Pt is c/c/c

Temp-97.6F

Bp: 110/90 mmhg 

PR: 82 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA. Coarse crepts + in RT ISA and MSA

P/A: soft,non tender

GRBS: 110 mg/dl

I/O: 900ml/550 ml

SPO2: 98% @ 4L O2

CNS: HMF INTACT


ABG:


PH: 7.323

PCO2: 38.3

PO2: 85.8

HCO3: 19.3






A:


ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).


with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs


With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)


With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)


with REFRACTORY HYPERKALEMIA ( RESOLVING).


With ANEMIA 



P:


Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD

Tab Shelcal  500 mg PO/OD


AMC bed 7, Unit 1

65/M

Day 6


S:

Facial puffiness +

Pedal edema +

SOB decreased

No fever spikes.


2 sessions of hemodialysis done 


O:

Pt is c/c/c

Temp-98.4F

Bp: 130/70 mmhg 

PR: 98 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA and ISA

P/A: soft,non tender

GRBS: 164 mg/dl

I/O: 800ml/950ml

SPO2: 98% @ 4L O2

CNS: HMF INTACT


ABG:


PH: 7.285

PCO2: 43.3

PO2: 127

HCO3: 19.9


HEMOGRAM 

Hb-7.0

TLC-5,700

PLC-1.5 lakhs 


 RFT 

Urea-97

Creat -4.1

UA-4.7

CA-8.0

PO4-3.8

Na-148

K-4.1

Cl-103 




A:


ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).


with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs


With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)


With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)


with REFRACTORY HYPERKALEMIA ( RESOLVED)


With ANEMIA 



P:


Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD

Tab Shelcal PO/OD

Plan for hemodialysis with PRBC transfusion


AMC bed 7, Unit 1

65/M

Day 7


S:

Pedal edema +

Facial puffiness+

(decreased since yesterday) 

SOB decreased

No fever spikes.

 

1 session of hemodialysis along with PRBC transfusion done yesterday.


Total 3 sessions of hemodialysis done 



O:

Pt is c/c/c

Temp-97.7F

Bp: 110/80 mmhg 

PR: 99 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA and ISA

P/A: soft,non tender

GRBS: 166 mg/dl

I/O: 1100ml /1000ml

SPO2: 99% @ RA

CNS: HMF INTACT


ABG:


PH: 7.26

PCO2: 56.4

PO2: 78.2

HCO3: 24.7


HEMOGRAM 

Hb-8.7

TLC-5,500

PLC-1.34 lakhs 


 RFT 

Urea-55

Creat -2.8

UA-3.3

Ca-9.8

PO4-3.0

Na-148

K-4.0

Cl-99



A:


ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).


with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs


With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)


With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)


with REFRACTORY HYPERKALEMIA ( RESOLVED)


With ANEMIA 



P:


Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD


AMC bed 7, Unit 1

65/M

Day 8


S:

Pedal edema +

Facial puffiness decreased 

SOB decreased

No fever spikes.

 

3 sessions of hemodialysis and 1 PRBC transfusion done



O:

Pt is c/c/c

Temp-98.6F

Bp: 110/70 mmhg 

PR: 86 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA and SSA

P/A: soft,non tender

GRBS: 155 mg/dl

I/O: 600 ml/ 800 ml

SPO2: 99% @ 4L O2

CNS: HMF INTACT


ABG: report pending 



HEMOGRAM 

Hb-7.4

TLC-4,900

PLC-1.25 lakhs 


 RFT 

Urea-53

Creat -2.8

UA-3.0

Ca-8.2

PO4-2.3

Na-149

K-3.3

Cl-105



A:


ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).


with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs


With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)


With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)


with REFRACTORY HYPERKALEMIA ( RESOLVED)


With ANEMIA 



P:


Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD



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